Vaccines have played a hugely important role in combating infectious diseases and are often touted as the most effective medical intervention to reduce morbidity and mortality caused by infectious diseases.
There is still a growing unmet need for effective vaccines for many persistent serious infectious diseases seen around the world. Vaccine development is often hindered by a lack of understanding of the immune responses explicitly required for protection, or by insufficient adjuvants and delivery systems to induce the necessary responses. Due to the many blueprints of a host immune response to a pathogen, there is a vast amount of knowledge generated across hosts, species, and pathogens. AI- and ML-derived insights can help draw parallels for creating better efficacious vaccines and the best antivirulence factors or adjuvants.
VaxMeldTM derives associations and insights between pathogens and a host response to identify novel antigenic targets and create immunological fingerprinting for generating efficacious vaccines.